Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study
Published: June 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.6131
Thomas V. Paul, Sivan Arul Selvan, Hesarghatta Shyamasunder Asha, Nihal Thomas, Krishnan Venkatesh, Anil Thomas Oommen, Thomas Mathai, Mandalamsubramanian Seshadri
1. Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.
2. Tutor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.
3. Assistant Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.
4. Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.
5. Professor, Department of Orthopedics, Christian Medical College, Vellore, India.
6. Associate Professor, Department of Orthopedics, Christian Medical College, Vellore, India.
7. Assistant Professor, Department of Orthopedics, Christian Medical College, Vellore, India.
8. Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore, India.
Correspondence
Dr. Thomas V. Paul,
Professor, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College, Vellore-632 004, India.
E-mail: thomasvpaul@yahoo.com
Background: Non-communicable diseases like hip fractures are a significant problem in a developing country like India. The risk factors for hip fractures vary according to local practices and the availability of preventive health care delivery systems. There is paucity of data on risk factors for hip fracture in the south Indian population.
Aim: This study was undertaken to assess risk factors associated with femoral neck (FN) fracture in South Indian postmenopausal women along with subsequent one year mortality.
Materials and Methods: One hundred four postmenopausal women with FN fracture and 104 age and BMI matched controls were included. Sedative use, visual impairment and other relevant risk factors were assessed. Bone biochemistry and Bone Mineral Density (BMD) were evaluated. A telephonic interview was done at the end of one year to ascertain the well-being.
Results: Sedative use, visual impairment, low FN BMD and vitamin-D deficiency (<20 ng/ml) were seen more in fracture subjects compared to controls (p=0.05). At the end of one year, 20% of the fracture subjects and 5% of the controls had died (p=0.001).
Conclusion:
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